7/14/2023 0 Comments Cashew allergy rashInitial diagnostic exams revealed a positive skin prick test to walnut (wheal mean diameter 5 mm same as histamine diameter) and specific IgE for cashew nut 21.1 kU/L walnut 10 kU/L hazelnut 2.94 kU/L, and almond 0.46 kU/L. The previous year she had an episode of labial swelling after ingesting a chocolate with hazelnut. Also, we emphasize the importance to latex sensitization with potential future clinical relevance and the sensitization to Hev b 3, which is not documented to be involved in cross-reactivity phenomena/latex–fruit syndrome or present in an otherwise healthy child.Ī 5-year-old Caucasian girl with no significant past medical history and with a family history of allergic disease (mother and 7-year-old brother with allergic rhinitis to pollens) was referred to Pediatric/Allergology Consultation after an episode of sialorrhea, perioral urticarial rash, tongue swelling, and immediate vomiting after oral contact with cashew nut. It is interesting that anaphylaxis was the first manifestation of allergy in a healthy child. ImmunoCAP ISAC was positive for storage proteins of walnut and hazelnut (Jug r 1 e Cor a 9) and for a specific allergen of latex (Hev b 3). Investigation revealed the following: positive skin prick test to walnut and positive specific IgE for cashew nut, walnut, hazelnut, and almond. We present the case of a previous healthy 5-year-old girl referred to Pediatric/Allergology Consultation after an episode of sialorrhea, perioral urticarial rash, tongue swelling, and immediate vomiting after oral contact with cashew nut. Cross-reactivity can occur not only with foods that are in the same biological family but also between certain fruits or vegetables and latex (latex–fruit syndrome). Food allergy affects many young children and tree nut allergy is accountable for a large number of severe, life-threatening anaphylactic reactions.
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